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Marijuana inspection: validation guidelines

Any method derived from a standard method or literature method requires validation showing that the method is fit to purpose. In the absence of standard methods, a single laboratory validation or equivalent is required to show that the method is fit for purpose in the intended matrix and, if applicable, that any modifications to the original method do not negatively impact performance. Method validation should, at a minimum, verify accuracy, precision, analytical sensitivity, analytical specificity, limit of detection, limit of quantification, reportable range and the identification of interfering substances. For microbiological methods adopted from a standard method, inclusivity/exclusivity does not require complete reassessment, provided that the referenced media, primers, probes, antibodies, critical chemistries, etc., were not modified.