Overdose prevention

About our program

The Colorado Department of Public Health and Environment receives funding from the Centers for Disease Control and Prevention and the Bureau of Justice Affairs, to address drug overdose. We work closely with other federal, state and local partners to accomplish the following:

  • Conduct public health surveillance of the drug overdose epidemic.

  • Work with the Department of Regulatory Agencies to make the Prescription Drug Monitoring Program (PDMP) easier to use for Colorado health care providers.

  • Support prevention in opioid misuse and overdose by using existing data to inform evidence-based public health approaches. Partner with organizations across the state to implement local, evidence-based, data-driven prevention initiatives to support prevention strategies. 

  • Align and leverage state resources dedicated to preventing drug overdoses.

Grants and funding

Comprehensive Opioid, Stimulant, and Substance Abuse Site-based Program (COSSAP) Grant Request for Applications: Deadline extended 4/2/21

The Overdose Prevention Unit is offering this Request for Applications (RFA) as a competitive funding opportunity to develop, implement, or expand comprehensive programs in response to illicit opioids, stimulants, or other substances of abuse in seven specific rural counties. 

  • The COSSAP funding opportunity will focus on seven (7) rural counties: Bent, Costilla, Crowley, Huerfano, Otero, Prowers, and Saguache. Funding is only available for agencies who have the capacity to provide services to community members in at least one (1) of the identified rural counties. We encourage collaboration between agencies and if applicable counties.
Application Deadline: Extension April 2, 2021, 11:59 p.m.
  • To apply: Download all RFA materials and information regarding questions here.

    • Review in the link above, the Final_RFA_COSSAP_Updated 3.12.21.  for RFA eligibility requirements, funding period and schedule of activities. 

    • Modification #1: It was discovered that the link to the narrative template was to an incorrect template. A new link to the Project Narrative template has been uploaded. Please use the attachment titled: Attachment C_Project Narrative Template_Updated 3.12.21  Please disregard the initial template.

    • A new Attachment has been updated to include the new deadline extension. Attachment A: RFA Cover Sheet and Signature_Updated 3.12.21

    • A new Attachment has been updated to include the new deadline extensionAttachment B: Application Checklist_ Updated 3.12.31

    • All attachments are linked here

    • Due to this error, the deadline has been extended from March 26 to April 2, 2021.

    • Grant Questions and Responses.


Harm Reduction Grant Fund 


Boulder County Public Health Department
Harm Reduction Action Center
Lakewood Police Department
Pitkin County Public Health
Southern Colorado Harm Reduction Association

Harm Reduction Program Manual 

You can also find the program manual at this link: https://drive.google.com/drive/folders/1TxIUoLdjb_Wp6h3FMZTExWkToDzuOIw2?usp=sharing

Overdose Data to Action Grant Fund


Boulder County Community Services
Denver Department of Public Health and Environment
Fremont County Public Health
Jefferson County Public Health
Mesa County Public Health
North Colorado Health Alliance
Otero County Public Health
Pueblo County Public Health
San Luis Valley Area Health Education Center
Sober AF Entertainment
Springs Recovery Connection

CDPHE Colorado Coroner Mini-Grant opportunity

The Colorado Department of Public Health and Environment's Opioid Overdose Prevention Program invites Colorado coroners\' offices to apply for mini-grants offered to support coroners as they deal with the opioid crisis in Colorado. Colorado coroners may apply for up to $5000 to support toxicology testing. Apply now.

Naloxone Bulk Purchase Fund opportunity 

Colorado Senate Bill 19-227 created the Opiate Antagonist- Naloxone Bulk Purchase Fund. It allows eligible entities to purchase opiate antagonists, such as naloxone or Narcan, at low or no cost. 

  • Eligible entities include, but are not limited to:  local public health agencies, school districts, law enforcement agencies, and entities with publicly accessible AEDs,  which include but are not limited to public universities, recreation centers, shopping centers, and workplaces. Ineligible entities: healthcare settings and pharmacies.

  • All eligible entities must have a current standing order in place prior to submitting an application.

Colorado Drug Overdose Dashboard

County and state-level data for Colorado from multiple sources, including detailed information about drug prescribing, non-fatal emergency department visits and hospitalizations, and drug overdose deaths, prepared by the Violence and Injury Prevention - Mental Health Promotion Branch and Overdose Prevention Unit.

Overdose prevention

Overdose treatment

  • Stop the Clock Colorado - Find out where to obtain Naloxone to treat a narcotic overdose in an emergency situation.

  • Naloxone standing orders - How pharmacies and harm reduction agencies can get Naloxone standing orders.

  • Opioid overdose - How to recognize and treat an overdose.

  • Find treatment for addiction - Colorado Department of Human Services, Office of Behavioral Health (OBH) Licensing and Designation Database and Electronic Records System (LADDERS) offers this referral resource for information and services for prevention, treatment and recovery from substance use and mental health conditions.


Contact our team

Email: odprevention@state.co.us