Colorado Antimicrobial Stewardship Endeavor (CASE)

CASE banner
cdphe, children's, and be antibiotics aware logos

About CASE: In August 2021, the Colorado Department of Public Health and Environment (CDPHE) partnered with Children’s Hospital Colorado to start the Colorado Antimicrobial Stewardship Endeavor (CASE). CASE includes physicians, pharmacists, and epidemiologists who provide mentorship and resources to Colorado hospitals that may be new to antibiotic stewardship. Antibiotic stewardship is the effort to measure and improve how antibiotics are prescribed by clinicians and used by patients. Improving antibiotic prescribing and use is critical to effectively treat infections, protect patients from harms caused by unnecessary antibiotic use, and combat antibiotic resistance. Learn more on the antimicrobial stewardship main page

Through a series of workshops and one-on-one consultations, CASE will support hospital antibiotic stewardship programs to:

  • Create evidence-based actions to improve antibiotic stewardship. 
  • Develop procedures to track and monitor antibiotic use and reporting.
  • Extend antibiotic stewardship activities to pediatric patients.
  • Develop programs that meet state and national standards and CDC’s Core Elements of Antibiotic Stewardship.
  • Interact with antimicrobial steward peers statewide.
  • Request one-on-one consultations from the CASE team.

CASE also seeks to provide resources such as treatment guidelines, support for reporting antibiotic use to the National Healthcare Safety Network (NHSN), and links to evidence-based guidelines and tools.

CASE workshops and office hours schedule

Workshop 1: Building Antimicrobial Stewardship Programs in resource limited community settings: November 18 noon - 1 p.m. MST

Office hour 1: December 5 noon - 1 p.m. MST
Workshop 2 Guideline development and adaptation: January 13th noon - 1 p.m MST Office hour 2: January 23rd noon - 1pm MST
Workshop 3 ASP Data Management and NHSN AU Module Basics: March 24 from noon - 1 p.m MST Office hour 3: March 27 noon - 1 p.m. MST
Workshop 4 The Intersection of Diagnostic and Antimicrobial Stewardship : May 19 noon - 1p.m MST Office hour 4: May 22 noon - 1 p.m. MST

Registration does not expire! Join us any time before the last session. 

CASE workshop guest speakers

May 19, 2023

Alyssa Yang Castillo, MD
Assistant Professor of Medicine, Division of Infectious Diseases, University of Colorado School of Medicine
Dr. Alyssa Castillo is an Assistant Professor at the University of Colorado. She works clinically in general infectious diseases and serves as the Associate Medical Director for Infection Prevention & Control at the University of Colorado Hospital. She completed her clinical fellowship training at the University of Washington, where she worked closely with the UW Center for Stewardship in Medicine (CSiM, formerly TASP) to provide specialty didactic education and support to stewardship programs in rural and critical access hospitals in the Northwest region. Her primary academic area of interest is diagnostic stewardship which intersects antimicrobial stewardship and infection prevention -- impacting both antimicrobial use and healthcare associated infection (HAI) diagnosis and metric reporting.
Matthew Miller, PharmD, BCIDP
Infectious Diseases and Antimicrobial Stewardship Clinical Pharmacy Specialist, Children’s Hospital Colorado,
Assistant Clinical Professor, University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences, and University of Colorado School of Medicine
"Matthew Miller is an experienced board-certified infectious diseases (ID) pharmacist who completed his PGY-2 at the University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences. He served as the pharmacy lead for the antimicrobial stewardship (AS) program at the University of Colorado Hospital until his transition to Children’s Hospital Colorado in October 2022 as an AS and ID clinical pharmacist. He is passionate about integrating diagnostics with AS initiatives, as well as antimicrobial dose optimization through application of PK-PD principles in special populations."


March 23, 2023

Christine MacBrayne PharmD, Antimicrobial Stewardship and Infectious Disease Clinical Pharmacist Specialist at Children’s Hospital Colorado Christine MacBrayne graduated from the University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences with her PharmD and went on to pursue a PGY-1 pharmacy practice residency at Children’s Hospital Colorado. Following residency, she completed a post-doctoral fellowship in antiviral pharmacokinetics at the University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences. She has been in her current role since 2017 and has completed various quality improvement training certificate courses to help guide her antimicrobial stewardship efforts.
Stacy Volk PharmD Stacy Volk is a clinical pharmacist specializing in antimicrobial stewardship and infectious diseases at Intermountain Health Lutheran Medical Center in Wheat Ridge, CO.  She is a graduate of the University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences and completed her PGY-1 pharmacy practice residency at the University of Louisville Hospital in Louisville, Kentucky.  She is a board certified infectious diseases pharmacist and is currently working to complete her Masters of Public Health degree from the University of Colorado School of Public Health.  Stacy has been in her current role since 2010 and has been working with NHSN AUR data since 2016 to help identify areas of opportunity to optimize antibiotic use at LMC

Jan. 13, 2023

Speaker Background
Leigh Anne Bakel, MD, MSc
Associate Professor of Pediatric Hospital Medicine, University of Colorado School of Medicine
Medical Director of Clinical Effectiveness and
Director of the Clinical Pathways Program, Children’s Hospital Colorado
Dr. Leigh Anne Bakel is a Pediatric Hospitalist at Children’s Hospital Colorado where she also serves as a Medical Director of Clinical Effectiveness, and the Director of the Clinical Pathways Program. Her masters in Clinical Epidemiology is backed by her extensive experience in research in clinical practice guidelines on an international level. She, with the help of the Clinical Effectiveness team, transformed the Clinical Pathways program using process improvement strategies. Her areas of academic interest are building a national collaborative of pediatric Clinical Pathway programs, improving implementation and dissemination of Clinical Pathways, and developing a Clinical Pathway Learning Health System to further improve outcomes for children.

Nov. 18, 2022

Alfredo J. Mena Lora, MD, FIDSA, FACP
Assistant Professor
University of Illinois Chicago, Saint Anthony Hospital
Alfredo J. Mena Lora, MD FIDSA is an assistant professor at the University of Illinois at Chicago, where he serves as Program Director for the Infectious Diseases fellowship and Associate Program Director for the Internal Medicine residency. He directs Infection Prevention and Antimicrobial Stewardship at Saint Anthony Hospital. Dr. Mena Lora has an interest in antimicrobial use and resistance in the United States and abroad.
Jessica Zering, PharmD, BCPS
Antimicrobial Stewardship Pharmacist
Washington State Department of Health
Jessica Zering is a board-certified pharmacist with more than five years of experience working in antimicrobial stewardship at a critical access hospital. The stewardship program that she created at Astria Sunnyside Hospital is nationally recognized. It was featured on the CDC/HRSA webinar titled “Enhancing Antibiotic Stewardship Programs in Critical Access Hospitals” in November 2021 and in the February 2022 edition of the Medicare Beneficiary Quality Improvement Project (MBQIP) publication. She is passionate about protecting patients and communities from the unwanted consequences of antimicrobial use.


Fall 2021

Speaker Background
Sarah Parker, MD CHCO Sarah Parker, MD is an Infectious Diseases attending pediatric physician and the Medical Director for Children's Hospital Colorado Antimicrobial Stewardship Program.
Christine MacBrayne, PharmD CHCO Christine MacBrayne, PharmD, MSCS, BCIDP is an Infectious Disease and Antimicrobial Stewardship Clinical Pharmacist Specialist at Children's Hospital Colorado.
Michael J. Bozzella, DO, MS CHCO Michael Bozzella, DO is an Infectious Diseases attending pediatric physician and Antimicrobial Steward at Children’s Hospital Colorado.
Matt Miller, PharmD CHCO
(previously UCHealth)
Matt Miller, PharmD is an Infectious Disease and Antimicrobial Stewardship Clinical Pharmacist at Children's Hospital Colorado. 
Rana Hamdy, MD, MPH, MSCE
Children’s National
Rana Hamdy, MD is an Infectious Disease Specialist and Investigator and the Director of the Antimicrobial Stewardship Program at Children's National Research Institute.
Marc Meyer, PharmD
Southwest Health System
Marc Meyer, PharmD is the Director Of Pharmacy Services and Infection Control and 340B Program at Southwest Health System.
Sarah Jung, PhD, D(ABMM)
Microbiology at CHCO
Sarah Jung, PhD is the Scientific Director of Clinical Microbiology at Children’s Hospital Colorado.
Jamey Atchison 
Microbiology at CHCO/Denver Health
Jamey Atchison is a Medical Technologist with Children’s Hospital Colorado.
Kathleen Martinez, MSN, RN, CPN
from IP/Epi at CHCO
Kathleen Martinez, BSN, MSN, RN, CPN is a Nurse in the Infection Prevention/Epidemiology Section at Children’s Hospital Colorado.
Heather Johnson, PharmD from CHCO Heather Johnson, PharmD is an Antimicrobial Stewardship team-member at Children’s Hospital Colorado.


Past workshops and presentations
Spring 2023 Presentation slides
Jan. 13, 2023 Guideline development and adaptation -  Presentation | Recording
March 24, 2023 ASP Data Management and NHSN AU Module Basics - Presentation | Recording
May 19, 2023 Intersection of Diagnostic and Antimicrobial Stewardship - Presentation | Recording


Spring 2022 Presentation slides
Jan. 21, 2022 Stewardship Part 1: Why, who, how to keep track, and who to ask 
Feb. 25, 2022 Stewardship Part 2: Pharmacy Power 
Apr. 22, 2022 Stewardship Part 3: It starts with a handshake
June 24, 2022 Stewardship Part 4: The Larger Team


Fall 2022 Presentation slides
Nov. 18, 2022 Stewardship in the community and critical access settings | Presentation video

CASE one-on-one consultations

People from our two teams work together to troubleshoot difficulties and help develop plans for improving your stewardship program over a 30-60 minute session. These sessions are tailored to your specific needs and situations. 

To schedule a session, email Michael J Bozzella DO MS (CASE Lead) at or CDPHE at